Recommendations regarding the rabbit posterolateral spinal fusion model

• The Performance of a Sterile Demineralized Bone Matrix Putty in a Rabbit Posterolateral Fusion Model

INTRODUCTION: Bone fusion, such as in spinal surgeries, may be accelerated through the use of a bone graft substitute (BGS). While autograft was considered the gold standard of treatment, it can be undesirable for use by surgeons due to donor site morbidity and limited availability. As an alternate method of treatment, human allograft Demineralized Bone Matrix (DBM) can be used by surgeons eith...

ENHANCING POSTEROLATERAL SPINAL FUSION WITH rhBMP-6 EXPOSED OSTEOPROGENITORCELLS

INTRODUCTION: The nonunion rate after posterolateral fusion has been reported to be as high as thirty-five percent, even with the use of autogenous iliac crest bone graft (ICBG) [4]. Accordingly, alternative techniques for expanding or stimulating the spinal fusion process are actively being investigated [1]. For the past several years we have been developing a strategy for stimulating marrow-d...

Assessment of Intergro Bone Graft Substitute in a Rabbit Posterolateral Fusion Model

Curb the Pain of Spondylolisthesis; Comparing Posterolateral Fusion with Posterior Lumbar Interbody Fusion

Background & Aim: The purpose of this study was to evaluate and compare the pain of patients with spondylolisthesis who had undergone either of the surgery techniques: posterolateral fusion (PLF) or posterior lumbar interbody fusion (PLIF). Methods & Materials/Patients: In a prospective observational study, 102 surgical candidates with low grade degenerative and isthmic spondylolisthesis were e...

Posterolateral inter-transverse lumbar fusion in a mouse model

BACKGROUND Spinal fusion is a common orthopaedic procedure that has been previously modeled using canine, lapine, and rodent subjects. Despite the increasing availability of genetically modified mouse strains, murine models have only been infrequently described. PURPOSE To present an efficient and minimally traumatic procedure for achieving spinal fusion in a mouse model and determine the opt...